Roughing Up Smoothened: Chemical Modulators of Hedgehog Signaling

DSpace/Manakin Repository

Roughing Up Smoothened: Chemical Modulators of Hedgehog Signaling

Citable link to this page

 

 
Title: Roughing Up Smoothened: Chemical Modulators of Hedgehog Signaling
Author: King, Randall Wharton
Citation: King, Randall W. 2002. Roughing up Smoothened: Chemical modulators of Hedgehog signaling. Journal of Biology 1(2): 8.
Full Text & Related Files:
Abstract: Small-molecule antagonists of Hedgehog-pathway signaling, such as cyclopamine, have been known for some time. Now, small-molecule agonists of the Hedgehog pathway have also been identified. The finding that both antagonists and agonists target the protein Smoothened supports the emerging hypothesis that Smoothened may be regulated by endogenous small molecules.
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137068/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10236192
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters