Show simple item record

dc.contributor.authorTropea, Kristen
dc.contributor.authorChristou, Helen A.
dc.date.accessioned2013-02-11T20:45:50Z
dc.date.issued2012
dc.identifier.citationTropea, Kristen, and Helen Christou. 2012. Current pharmacologic approaches for prevention and treatment of bronchopulmonary dysplasia. International Journal of Pediatrics 2012.en_US
dc.identifier.issn1687-9740en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10288494
dc.description.abstractBronchopulmonary dysplasia (BPD) is a major complication of preterm birth and has serious adverse long-term health consequences. The etiology of BPD is complex, multifactorial, and incompletely understood. Contributing factors include ventilator-induced lung injury, exposure to toxic oxygen levels, and infection. Several preventive and therapeutic strategies have been developed with variable success. These include lung protective ventilator strategies and pharmacological and nutritional interventions. These strategies target different components and stages of the disease process and they are commonly used in combination. The purpose of this review is to discuss the evidence for current pharmacological interventions and identify future therapeutic modalities that appear promising in the prevention and management of BPD. Continued improved understanding of BPD pathogenesis leads to opportunities for newer preventive approaches. These will need to be evaluated in the setting of current clinical practice in order to assess their efficacy.en_US
dc.language.isoen_USen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.isversionofdoi:10.1155/2012/598606en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259479/pdf/en_US
dash.licenseLAA
dc.titleCurrent Pharmacologic Approaches for Prevention and Treatment of Bronchopulmonary Dysplasiaen_US
dc.typeCommentary or Reviewen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalInternational Journal of Pediatricsen_US
dash.depositing.authorChristou, Helen A.
dc.date.available2013-02-11T20:45:50Z
dc.identifier.doi10.1155/2012/598606*
dash.contributor.affiliatedLeeman, Kristen
dash.contributor.affiliatedChristou, Helen


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record