The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12

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The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12

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Title: The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12
Author: Fang, Jiliang; Zhou, Kehua; Hong, Yang; Wang, Lei; Xue, Chao; Liu, Baoyan; Wang, Xiaoling; Liu, Hesheng; Wang, Yin; Liu, Jun; Song, Ming; Zhu, Bing

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Citation: Fang, Jiliang, Xiaoling Wang, Hesheng Liu, Yin Wang, Kehua Zhou, Yang Hong, Jun Liu, et al. 2012. The limbic-prefrontal network modulated by electroacupuncture at CV4 and CV12. Evidence-Based Complementary and Alternative Medicine 2012:515893.
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Abstract: fMRI studies showed that acupuncture could induce hemodynamic changes in brain networks. Many of these studies focused on whether specific acupoints could activate specific brain regions and were often limited to manual acupuncture at acupoints on the limbs. In this fMRI study, we investigated acupuncture's modulation effects on brain functional networks by electroacupuncture (EA) at acupoints on the midline of abdomen. Acupoints Guanyuan (CV4) and Zhongwan (CV12) were stimulated in 21 healthy volunteers. The needling sensations, brain activation, and functional connectivity were studied. We found that the limbic-prefrontal functional network was deactivated by EA at CV4 and CV12. More importantly, the local functional connectivity was significantly changed during EA stimulation, and the change persisted during the period after the stimulation. Although minor differences existed, both acupoints similarly modulated the limbic-prefrontal functional network, which is overlapped with the functional circuits associated with emotional and cognitive regulation.
Published Version: doi:10.1155/2012/515893
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265182/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10288829
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