Left Ventricular Remodeling Following Myocardial Infarction Revealed with a Quantitative Diffusion MRI Tractography Framework

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Left Ventricular Remodeling Following Myocardial Infarction Revealed with a Quantitative Diffusion MRI Tractography Framework

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Title: Left Ventricular Remodeling Following Myocardial Infarction Revealed with a Quantitative Diffusion MRI Tractography Framework
Author: Thiagalingam, Aravinda; Maurovich-Horvat, Pal; Jackowski, Marcel P; Mekkaoui, Choukri; Huang, Shuning; Dai, Guangping; Reese, Timothy G.; Ruskin, Jeremy Neil; Hoffmann, Udo; Sosnovik, David E.

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Citation: Mekkaoui, Choukri, Shuning Huang, Guangping Dai, Timothy G. Reese, Aravinda Thiagalingam, Pal Maurovich-Horvat, Jeremy Ruskin, Udo Hoffmann, Marcel P. Jackowski, and David E. Sosnovik. 2012. Left ventricular remodeling following myocardial infarction revealed with a quantitative diffusion MRI tractography framework. Journal of Cardiovascular Magnetic Resonance 14(Suppl. 1): P35.
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Abstract: A cardiac-tailored framework for 3D Diffusion Tensor MRI tractography is developed and used to characterize myofiber architecture in normal and remodeled myocardium. We show that myofibers in the subepicardium of the remote infarct zone become less oblique (more circumferential) as the heart dilates and remodels. This fiber realignment may play an important role in the loss of contractile function in the remote zone over time.
Published Version: doi:10.1186/1532-429X-14-S1-P35
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304826/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10318203
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