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dc.contributor.authorSebastiani, Paola
dc.contributor.authorSolovieff, Nadia
dc.contributor.authorSun, Jenny X.
dc.date.accessioned2013-02-22T15:35:31Z
dc.date.issued2012
dc.identifier.citationSebastiani, Paola, Nadia Solovieff, and Jenny X. Sun. 2012. Naïve Bayesian classifier and genetic risk score for genetic risk prediction of a categorical trait: Not so different after all! Frontiers in Genetics 3:26.en_US
dc.identifier.issn1664-8021en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10332596
dc.description.abstractOne of the most popular modeling approaches to genetic risk prediction is to use a summary of risk alleles in the form of an unweighted or a weighted genetic risk score, with weights that relate to the odds for the phenotype in carriers of the individual alleles. Recent contributions have proposed the use of Bayesian classification rules using Naïve Bayes classifiers. We examine the relation between the two approaches for genetic risk prediction and show that the methods are mathematically related. In addition, we study the properties of the two approaches and describe how they can be generalized to include various models of inheritance.en_US
dc.language.isoen_USen_US
dc.publisherFrontiers Research Foundationen_US
dc.relation.isversionofdoi:10.3389/fgene.2012.00026en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289795/pdf/en_US
dash.licenseLAA
dc.titleNaïve Bayesian Classifier and Genetic Risk Score for Genetic Risk Prediction of a Categorical Trait: Not So Different After All!en_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalFrontiers in Geneticsen_US
dash.depositing.authorSolovieff, Nadia
dc.date.available2013-02-22T15:35:31Z
dc.identifier.doi10.3389/fgene.2012.00026*
dash.contributor.affiliatedSolovieff, Nadia


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