Fiber Four-Wave Mixing Source for Coherent Anti-Stokes Raman Scattering Microscopy

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Fiber Four-Wave Mixing Source for Coherent Anti-Stokes Raman Scattering Microscopy

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Title: Fiber Four-Wave Mixing Source for Coherent Anti-Stokes Raman Scattering Microscopy
Author: Lefrancois, Simon; Fu, Dan; Holtom, Gary R.; Kong, Lingjie; Wadsworth, William J.; Schneider, Patrick; Herda, Robert; Zach, Armin; Xie, Xiaoliang Sunney; Wise, Frank W.

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Citation: Lefrancois, Simon, Dan Fu, Gary R. Holtom, Lingjie Kong, William J. Wadsworth, Patrick Schneider, Robert Herda, Armin Zach, X. Sunney Xie, and Frank W. Wise. 2012. Fiber four-wave mixing source for coherent anti-strokes Raman scattering microscopy. Optics Letters 37(10): 1652-54.
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Abstract: We present a fiber-format picosecond light source for coherent anti-Stokes Raman scattering microscopy. Pulses from an Yb-doped fiber amplifier are frequency-converted by four-wave mixing in normal dispersion photonic crystal fiber to produce a synchronized two-color picosecond pulse train. We show that seeding the four-wave mixing process overcomes the deleterious effects of group-velocity mismatch and allows efficient conversion into narrow frequency bands. The source generates more than 160 mW of nearly-transform-limited pulses tunable from 775 to 815 nm. High-quality coherent Raman images of animal tissues and cells acquired with this source are presented.
Published Version: http://dx.doi.org/10.1364/OL.37.001652
Other Sources: www.ncbi.nlm.nih.gov/pubmed/22627526
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10386978
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