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dc.contributor.authorWible, Cynthia Gayle
dc.date.accessioned2013-03-29T19:35:16Z
dc.date.issued2012
dc.identifier.citationWible, Cynthia Gayle. 2012. Schizophrenia as a disorder of social communication. Schizophrenia Research and Treatment 2012:920485.en_US
dc.identifier.issn2090-2085en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10482563
dc.description.abstractEvidence is reviewed for the existence of a core system for moment-to-moment social communication that is based on the perception of dynamic gestures and other social perceptual processes in the temporal-parietal occipital junction (TPJ), including the posterior superior temporal sulcus (PSTS) and surrounding regions. Overactivation of these regions may produce the schizophrenic syndrome. The TPJ plays a key role in the perception and production of dynamic social, emotional, and attentional gestures for the self and others. These include dynamic gestures of the body, face, and eyes as well as audiovisual speech and prosody. Many negative symptoms are characterized by deficits in responding within these domains. Several properties of this system have been discovered through single neuron recording, brain stimulation, neuroimaging, and the study of neurological impairment. These properties map onto the schizophrenic syndrome. The representation of dynamic gestures is multimodal (auditory, visual, and tactile), matching the predominant hallucinatory categories in schizophrenia. Inherent in the perceptual signal of gesture representation is a computation of intention, agency, and anticipation or expectancy (for the self and others). The neurons are also tuned or biased to rapidly detect threat-related emotions. I review preliminary evidence that overactivation of this system can result in schizophrenia.en_US
dc.language.isoen_USen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.isversionofdoi:10.1155/2012/920485en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420370/pdf/en_US
dash.licenseLAA
dc.titleSchizophrenia as a Disorder of Social Communicationen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalSchizophrenia Research and Treatmenten_US
dash.depositing.authorWible, Cynthia Gayle
dc.date.available2013-03-29T19:35:16Z
dc.identifier.doi10.1155/2012/920485*
dash.contributor.affiliatedWible, Cynthia Gayle


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