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dc.contributor.authorDowdall, Jayme R.
dc.contributor.authorOpfermann, Krisha J.
dc.contributor.authorKim, Harold
dc.contributor.authorLin, Ho-Sheng
dc.date.accessioned2013-03-29T19:42:04Z
dc.date.issued2012
dc.identifier.citationDowdall, Jayme R., Krisha J. Opfermann, Harold Kim, and Ho-Sheng Lin. 2012. A case of radiation-induced multifocal laryngeal angiosarcoma presenting as a diagnostic dilemma. Case Reports in Otolaryngology 2012:139310.en_US
dc.identifier.issn2090-6765en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10482566
dc.description.abstractHead and neck sarcomas are relatively rare tumors, with angiosarcomas representing a small subset. Angiosarcoma is a malignant endothelial neoplasm characterized by atypical, multilayered, or solid endothelial proliferation with vasoformative architecture. The global incidence of irradiation-associated sarcoma is estimated as between 0.03% and 0.08%. Here we reported the case of an elderly woman previously treated with radiation more than 20 years ago for an unknown primary of head and neck. This interesting case presented as a diagnostic challenge, and multiple biopsies were required to eventually establish the diagnosis of laryngeal angiosarcoma. We additionally have confirmation from our prior radiation records that the patient did, in fact, receive a substantial dose of radiation to the site previously. To our knowledge, this case represents the first report of a documented radiation-induced multifocal laryngeal angiosarcoma.en_US
dc.language.isoen_USen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.isversionofdoi:10.1155/2012/139310en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424656/pdf/en_US
dash.licenseLAA
dc.titleA Case of Radiation-Induced Multifocal Laryngeal Angiosarcoma Presenting as a Diagnostic Dilemmaen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalCase Reports in Otolaryngologyen_US
dash.depositing.authorDowdall, Jayme R.
dc.date.available2013-03-29T19:42:04Z
dc.identifier.doi10.1155/2012/139310*
dash.contributor.affiliatedDowdall, Jayme R.


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