Therapeutic Interventions against Inflammatory and Angiogenic Mediators in Proliferative Diabetic Retinopathy

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Therapeutic Interventions against Inflammatory and Angiogenic Mediators in Proliferative Diabetic Retinopathy

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Title: Therapeutic Interventions against Inflammatory and Angiogenic Mediators in Proliferative Diabetic Retinopathy
Author: Gologorsky, Daniel; Thanos, Aristomenis; Vavvas, Demetrios

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Citation: Gologorsky, Daniel, Aristomenis Thanos, and Demetrios Vavvas. 2012. Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy. Mediators of Inflammation 2012:629452.
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Abstract: The global prevalence of diabetes is estimated to be 336 million people, with diabetic complications contributing to significant worldwide morbidity and mortality. Diabetic retinopathy results from cumulative microvascular damage to the retina and inflammation is recognized as a critical driver of this disease process. This paper outlines the pathophysiology leading to proliferative diabetic retinopathy and highlights many of the inflammatory, angiogenic, and cytokine mediators implicated in the development and progression of this disease. We focus a detailed discussion on the current targeted therapeutic interventions used to treat diabetic retinopathy.
Published Version: doi:10.1155/2012/629452
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457666/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10522935
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