Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data

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Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data

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Title: Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data
Author: Strutton, David R; Farkouh, Raymond A; Rubin, Jaime L; McGarry, Lisa J; Loiacono, Paul M; Klugman, Keith P; Pelton, Steven I; Gilmore, Kristen E; Weinstein, Milton C.

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Citation: Strutton, David R, Raymond A Farkouh, Jaime L Rubin, Lisa J McGarry, Paul M Loiacono, Keith P Klugman, Steven I Pelton, Kristen E Gilmore, and Milton C Weinstein. 2012. Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data. BMC Infectious Diseases 12: 175.
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Abstract: Background: Analysis of US claims data from April 2010 to June 2011 estimated that 39% of the 13-valent pneumococcal conjugate vaccine (PCV13) catch-up eligible cohort would ever receive the catch-up vaccination; a previous analysis assumed 87%. Methods: This updated figure was applied to a previously published 10-year Markov model while holding all other inputs constant. Results: Our model estimated that the catch-up program as currently implemented is estimated to prevent an additional 1.7 million cases of disease in children aged ≤59 months over a 10-year period, compared with routine PCV13 vaccination with no catch-up program. Conclusions: Because 39% catch-up uptake is less than the level of completion of the 4-dose primary PCV13 series, vaccine-preventable cases of pneumococcal disease and related deaths could be decreased further with additional uptake of catch-up vaccination in the catch-up eligible cohort.
Published Version: doi:10.1186/1471-2334-12-175
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426485/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10578930
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