High-throughput approaches to discover novel immunomodulatory agents for cancer

 
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https://doi.org/10.4161/onci.21058
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McMillin, Douglas William, and Constantine S. Mitsiades. 2012. High-throughput approaches to discover novel immunomodulatory agents for cancer. Oncoimmunology 1(8): 1406-1408.
Abstract
The clinical success of immunomodulatory thalidomide derivatives has renewed the general interest in immunomodulatory anticancer compounds and prompted us to develop a high-throughput system to quantify immune effector-cell activity. We documented that the interaction between cancer cells, their stroma, anticancer agents and cells from the innate system are critical for determining the response of tumors to immunomodulatory strategies.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518518/pdf/
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http://nrs.harvard.edu/urn-3:HUL.InstRepos:10581973

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