# Alcohol Intake and Mortality among Women with Invasive Breast Cancer

 Title: Alcohol Intake and Mortality among Women with Invasive Breast Cancer Author: Harris, Holly Ruth; Bergkvist, L; Wolk, A Note: Order does not necessarily reflect citation order of authors. Citation: Harris, Holly Ruth, L. Bergkvist, and A. Wolk. 2012. Alcohol intake and mortality among women with invasive breast cancer. British Journal of Cancer 106: 592-595. Full Text & Related Files: 3273342.pdf (188.5Kb; PDF) Abstract: Background: Alcohol intake has consistently been associated with increased breast cancer incidence in epidemiological studies. However, the relation between alcohol and survival after breast cancer diagnosis is less clear. Methods: We investigated whether alcohol intake was associated with survival among 3146 women diagnosed with invasive breast cancer in the Swedish Mammography Cohort. Alcohol consumption was estimated using a food frequency questionnaire. Cox proportional hazard models were used to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs). Results: From 1987 to 2008 there were 385 breast cancer-specific deaths and 860 total deaths. No significant association was observed between alcohol intake and breast cancer-specific survival. Women who consumed 10 g per day (corresponding to approximately 0.75 to 1 drinks) or more of alcohol had an adjusted HR (95% CI) of breast cancer-specific death of 1.36 (0.82–2.26;p$$_{trend}$$=0.47) compared with non-drinkers. A significant inverse association was observed between alcohol and non-breast cancer deaths. Those who consumed 3.4–9.9 g per day of alcohol had a 33% lower risk of death compared with non-drinkers (95% CI 0.50–0.90;p$$_{trend}$$=0.04). Conclusion: Our findings suggest that alcohol intake up to approximately one small drink per day does not negatively impact breast cancer-specific survival and a half drink per day is associated with a decreased risk of mortality from other causes. Published Version: doi:10.1038/bjc.2011.561 Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273342/pdf/ Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10611785 Downloads of this work: