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dc.contributor.authorHarris, Holly Ruth
dc.contributor.authorBergkvist, L
dc.contributor.authorWolk, A
dc.date.accessioned2013-05-07T18:05:39Z
dc.date.issued2012
dc.identifier.citationHarris, Holly Ruth, L. Bergkvist, and A. Wolk. 2012. Alcohol intake and mortality among women with invasive breast cancer. British Journal of Cancer 106: 592-595.en_US
dc.identifier.issn0007-0920en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10611785
dc.description.abstractBackground: Alcohol intake has consistently been associated with increased breast cancer incidence in epidemiological studies. However, the relation between alcohol and survival after breast cancer diagnosis is less clear. Methods: We investigated whether alcohol intake was associated with survival among 3146 women diagnosed with invasive breast cancer in the Swedish Mammography Cohort. Alcohol consumption was estimated using a food frequency questionnaire. Cox proportional hazard models were used to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs). Results: From 1987 to 2008 there were 385 breast cancer-specific deaths and 860 total deaths. No significant association was observed between alcohol intake and breast cancer-specific survival. Women who consumed 10 g per day (corresponding to approximately 0.75 to 1 drinks) or more of alcohol had an adjusted HR (95% CI) of breast cancer-specific death of 1.36 (0.82–2.26;p\(_{trend}\)=0.47) compared with non-drinkers. A significant inverse association was observed between alcohol and non-breast cancer deaths. Those who consumed 3.4–9.9 g per day of alcohol had a 33% lower risk of death compared with non-drinkers (95% CI 0.50–0.90;p\(_{trend}\)=0.04). Conclusion: Our findings suggest that alcohol intake up to approximately one small drink per day does not negatively impact breast cancer-specific survival and a half drink per day is associated with a decreased risk of mortality from other causes.en_US
dc.language.isoen_USen_US
dc.publisherNature Publishing Groupen_US
dc.relation.isversionofdoi:10.1038/bjc.2011.561en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273342/pdf/en_US
dash.licenseLAA
dc.subjectalcoholen_US
dc.subjectbreast canceren_US
dc.subjectsurvivalen_US
dc.titleAlcohol Intake and Mortality among Women with Invasive Breast Canceren_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalBritish Journal of Canceren_US
dash.depositing.authorHarris, Holly Ruth
dc.date.available2013-05-07T18:05:39Z
dc.identifier.doi10.1038/bjc.2011.561*
dash.contributor.affiliatedHarris, Holly R.


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