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dc.contributor.authorMalik, Vasanti
dc.contributor.authorFung, Teresa Toiyee
dc.contributor.authorvan Dam, Rob M.
dc.contributor.authorRimm, Eric B.
dc.contributor.authorRosner, Bernard Alfred
dc.contributor.authorHu, Frank B.
dc.date.accessioned2013-05-08T13:42:22Z
dc.date.issued2012
dc.identifier.citationMalik, Vasanti, Teresa Toiyee Fung, Rob M. van Dam, Eric B. Rimm, Bernard Alfred Rosner, and Frank B. Hu. 2012. Dietary patterns during adolescence and risk of type 2 diabetes in middle-aged women. Diabetes Care 35(1): 12-18.en_US
dc.identifier.issn0149-5992en_US
dc.identifier.issn1935-5548en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10612549
dc.description.abstractObjective: Whether dietary habits early in life can affect risk of type 2 diabetes (T2DM) in adulthood is unknown. We evaluated the relationship between dietary patterns during adolescence and risk of T2DM in midlife. Research design and methods: We examined the 7-year incidence of T2DM in relation to dietary patterns during high school among 37,038 participants in the Nurses’ Health Study II cohort, who completed a food-frequency questionnaire about their diet during high school. Dietary patterns were derived by factor analysis. Cox proportional hazards regression was used to estimate relative risk (RR) and 95% CI. Results: The prudent pattern, characterized by healthy foods, was not associated with risk of T2DM. The Western pattern, characterized by desserts, processed meats, and refined grains, was associated with 29% greater risk of T2DM (RR 1.29; 95% CI 1.00–1.66; P trend 0.04), after adjusting for high school and adult risk factors comparing extreme quintiles, but was attenuated after adjusting for adult weight change (1.19; 0.92–1.54). Women who had high Western pattern scores in high school and adulthood had an elevated risk of T2DM compared with women who had consistent low scores (1.82; 1.35–2.45), and this association was partly mediated by adult BMI (1.15; 0.85–1.56). Conclusions: A Western dietary pattern during adolescence may increase risk of T2DM in later life, partly through adult weight gain. Preventive measures should be aimed at developing healthy dietary habits that begin in early life and continue through adulthood.en_US
dc.language.isoen_USen_US
dc.publisherAmerican Diabetes Associationen_US
dc.relation.isversionofdoi:10.2337/dc11-0386en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241320/pdf/en_US
dash.licenseLAA
dc.subjectClinical Careen_US
dc.subjectEducationen_US
dc.subjectNutritionen_US
dc.subjectPsychosocial Researchen_US
dc.titleDietary Patterns during Adolescence and Risk of Type 2 Diabetes in Middle-Aged Womenen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalDiabetes Careen_US
dash.depositing.authorMalik, Vasanti
dc.date.available2013-05-08T13:42:22Z
dc.identifier.doi10.2337/dc11-0386*
dash.contributor.affiliatedFung, Teresa
dash.contributor.affiliatedVan Dam, Rob
dash.contributor.affiliatedMalik, Vasanti
dash.contributor.affiliatedRimm, Eric
dash.contributor.affiliatedRosner, Bernard
dash.contributor.affiliatedHu, Frank


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