Complicated Intra-Abdominal Infections in a Worldwide Context: An Observational Prospective Study (CIAOW Study)

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Complicated Intra-Abdominal Infections in a Worldwide Context: An Observational Prospective Study (CIAOW Study)

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Title: Complicated Intra-Abdominal Infections in a Worldwide Context: An Observational Prospective Study (CIAOW Study)
Author: Sartelli, Massimo; Catena, Fausto; Ansaloni, Luca; Moore, Ernest; Malangoni, Mark; Coimbra, Raul; Koike, Kaoru; Leppaniemi, Ari; Biffl, Walter; Balogh, Zsolt; Bendinelli, Cino; Kluger, Yoram; Agresta, Ferdinando; Di Saverio, Salomone; Tugnoli, Gregorio; Jovine, Elio; Ordonez, Carlos; Gomes, Carlos Augusto; Junior, Gerson Alves Pereira; Yuan, Kuo-Ching; Bala, Miklosh; Cui, Yunfeng; Marwah, Sanjay; Zachariah, Sanoop; Sakakushev, Boris; Kong, Victor; Ahmed, Adamu; Abbas, Ashraf; Gonsaga, Ricardo Alessandro Teixeira; Guercioni, Gianluca; Vettoretto, Nereo; Poiasina, Elia; Ben-Ishay, Offir; Díaz-Nieto, Rafael; Massalou, Damien; Skrovina, Matej; Gerych, Ihor; Augustin, Goran; Kenig, Jakub; Khokha, Vladimir; Tranà, Cristian; Kok, Kenneth Yuh Yen; Mefire, Alain Chichom; Hong, Suk-Kyung; Lohse, Helmut Alfredo Segovia; Ghnnam, Wagih; Verni, Alfredo; Lohsiriwat, Varut; Siribumrungwong, Boonying; Tavares, Alberto; Baiocchi, Gianluca; Das, Koray; Jarry, Julien; Zida, Maurice; Sato, Norio; Murata, Kiyoshi; Shoko, Tomohisa; Irahara, Takayuki; Hamedelneel, Ahmed O; Naidoo, Noel; Adesunkanmi, Abdul Rashid Kayode; Kobe, Yoshiro; Attri, AK; Sharma, Rajeev; Coccolini, Federico; El Zalabany, Tamer; Khalifa, Khalid Al; Sanjuan, Juan; Barnabé, Rita; Ishii, Wataru; Velmahos, George; Gupta, Sanjay; Peev, Miroslav P; Lee, Jae Gil

Note: Order does not necessarily reflect citation order of authors.

Citation: Sartelli, Massimo, Fausto Catena, Luca Ansaloni, Ernest Moore, Mark Malangoni, George Velmahos, Raul Coimbra, et al. 2013. Complicated intra-abdominal infections in a worldwide context: An observational prospective study (CIAOW Study). World Journal of Emergency Surgery 8:1.
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Abstract: Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18–98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients. The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.
Published Version: doi:10.1186/1749-7922-8-1
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