The Massachusetts General Hospital Acute Stroke Imaging Algorithm: An Experience and Evidence Based Approach

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The Massachusetts General Hospital Acute Stroke Imaging Algorithm: An Experience and Evidence Based Approach

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Title: The Massachusetts General Hospital Acute Stroke Imaging Algorithm: An Experience and Evidence Based Approach
Author: Gonzalez, Ramon Gilberto; Copen, William Alan; Schaefer, Pamela Whitney; Lev, Michael Howard; Pomerantz, Stuart R.; Rapalino, Otto; Chen, John Wen-Yueh; Hunter, George; Romero, Javier M.; Buchbinder, Bradley R.; Larvie, Mykol; Hirsch, Joshua A.; Gupta, Rajiv

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Citation: Gonzalez, Ramon Gilberto, William Alan Copen, Pamela Whitney Schaefer, Michael Howard Lev, Stuart R. Pomerantz, Otto Rapalino, John Wen-Yueh Chen, et al. 2013. The Massachusetts General Hospital acute stroke imaging algorithm: An experience and evidence based approach. Journal of Neurointerventional Surgery 5(Suppl 1): i7-i12.
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Abstract: The Massachusetts General Hospital Neuroradiology Division employed an experience and evidence based approach to develop a neuroimaging algorithm to best select patients with severe ischemic strokes caused by anterior circulation occlusions (ACOs) for intravenous tissue plasminogen activator and endovascular treatment. Methods found to be of value included the National Institutes of Health Stroke Scale (NIHSS), non-contrast CT, CT angiography (CTA) and diffusion MRI. Perfusion imaging by CT and MRI were found to be unnecessary for safe and effective triage of patients with severe ACOs. An algorithm was adopted that includes: non-contrast CT to identify hemorrhage and large hypodensity followed by CTA to identify the ACO; diffusion MRI to estimate the core infarct; and NIHSS in conjunction with diffusion data to estimate the clinical penumbra.
Published Version: doi:10.1136/neurintsurg-2013-010715
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623036/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10978158
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