Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons

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Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons

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Title: Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons
Author: Mardinly, Alan Robert
Citation: Mardinly, Alan Robert. 2013. Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons. Doctoral dissertation, Harvard University.
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Abstract: Neuronal activity and subsequent calcium influx activates a signaling cascade that causes transcription factors in the nucleus to rapidly induce an early-response program of gene expression. This early-response program is composed of transcriptional regulators that in turn induce transcription of late-response genes, which are enriched for regulators of synaptic development and plasticity that act locally at the synapse.
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11151534
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