Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons

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Title:	Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons
Author:	Mardinly, Alan Robert
Citation:	Mardinly, Alan Robert. 2013. Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons. Doctoral dissertation, Harvard University.
Full Text & Related Files:	Mardinly_gsas.harvard_0084L_10739.pdf (11.26Mb; PDF)
Abstract:	Neuronal activity and subsequent calcium influx activates a signaling cascade that causes transcription factors in the nucleus to rapidly induce an early-response program of gene expression. This early-response program is composed of transcriptional regulators that in turn induce transcription of late-response genes, which are enriched for regulators of synaptic development and plasticity that act locally at the synapse.
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Citable link to this page:	http://nrs.harvard.edu/urn-3:HUL.InstRepos:11151534
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