dc.contributor.advisor | Greenberg, Michael Eldon | |
dc.contributor.author | Mardinly, Alan Robert | |
dc.date.accessioned | 2013-10-08T17:32:06Z | |
dash.embargo.terms | 2014-06-07 | en_US |
dash.embargo.terms | 2014-06-07 | |
dc.date.issued | 2013-10-08 | |
dc.date.submitted | 2013 | |
dc.identifier.citation | Mardinly, Alan Robert. 2013. Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons. Doctoral dissertation, Harvard University. | en_US |
dc.identifier.other | http://dissertations.umi.com/gsas.harvard:10739 | en |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:11151534 | |
dc.description.abstract | Neuronal activity and subsequent calcium influx activates a signaling cascade that causes transcription factors in the nucleus to rapidly induce an early-response program of gene expression. This early-response program is composed of transcriptional regulators that in turn induce transcription of late-response genes, which are enriched for regulators of synaptic development and plasticity that act locally at the synapse. | en_US |
dc.language.iso | en_US | en_US |
dash.license | LAA | |
dc.subject | Neurosciences | en_US |
dc.subject | Activity | en_US |
dc.subject | Inhibition | en_US |
dc.subject | Npas4 | en_US |
dc.subject | somatostatin | en_US |
dc.subject | synapse development | en_US |
dc.title | Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons | en_US |
dc.type | Thesis or Dissertation | en_US |
dash.depositing.author | Mardinly, Alan Robert | |
dc.date.available | 2014-06-07T07:30:48Z | |
thesis.degree.date | 2013 | en_US |
thesis.degree.discipline | Biology: Medical Sciences, Division of | en_US |
thesis.degree.grantor | Harvard University | en_US |
thesis.degree.level | doctoral | en_US |
thesis.degree.name | Ph.D. | en_US |
dc.contributor.committeeMember | Chen, Chinfei | en_US |
dc.contributor.committeeMember | Hensch, Takao | en_US |
dc.contributor.committeeMember | Fishell, Gordon | en_US |
dash.contributor.affiliated | Mardinly, Alan Robert | |