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dc.contributor.advisorFontana, Walter
dc.contributor.authorStroustrup, Nicholas Edward
dc.date.accessioned2013-10-08T21:08:56Z
dash.embargo.terms2015-06-07en_US
dash.embargo.terms2015-06-07
dc.date.issued2013-10-08
dc.date.submitted2013
dc.identifier.citationStroustrup, Nicholas Edward. 2013. The C. elegans Lifespan Machine and its application to the temperature scaling of lifespan. Doctoral dissertation, Harvard University.en_US
dc.identifier.otherhttp://dissertations.umi.com/gsas.harvard:10801en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11158238
dc.description.abstractLifespan results from the complex interaction between genetic, environmental and stochastic factors, and therefore varies widely even among isogenic individuals. In C. elegans , the action of molecular mechanisms on aging can be inferred from their statistical effects on the distribution of lifespans within populations. However, such investigations are hindered by limitations in the methods available for collecting lifespan data. To enable the rapid collection of survival curves at any desired statistical resolution, we developed an automated platform for determining the lifespans of large populations of nematodes.en_US
dc.language.isoen_USen_US
dash.licenseLAA
dc.subjectAgingen_US
dc.titleThe C. elegans Lifespan Machine and its application to the temperature scaling of lifespanen_US
dc.typeThesis or Dissertationen_US
dash.depositing.authorStroustrup, Nicholas Edward
dc.date.available2015-06-08T07:30:33Z
thesis.degree.date2013en_US
thesis.degree.disciplineSystems Biologyen_US
thesis.degree.grantorHarvard Universityen_US
thesis.degree.leveldoctoralen_US
thesis.degree.namePh.D.en_US
dc.contributor.committeeMemberMurray, Andrewen_US
dc.contributor.committeeMemberKishony, Royen_US
dc.contributor.committeeMemberRuvkun, Garyen_US
dc.contributor.committeeMemberSlack, Franken_US
dash.contributor.affiliatedStroustrup, Nicholas Edward


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