The landscape of somatic mutations in primary prostate adenocarcinoma

Baca, Sylvan Charles

Citation

Baca, Sylvan Charles. 2013. The landscape of somatic mutations in primary prostate adenocarcinoma. Doctoral dissertation, Harvard University.

Abstract

Prostate cancer is the second leading cause of cancer deaths among men. Targeted analyses of DNA from prostate cancers have identified recurrent somatic alterations that promote tumor growth and survival. Only recently, however, has the comprehensive analysis of cancer genomes become possible due to rapid advances in DNA sequencing technology.

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