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dc.contributor.advisorSabeti, Pardis Christine
dc.contributor.authorPark, Daniel John
dc.date.accessioned2013-10-14T14:50:07Z
dc.date.issued2013-10-14
dc.date.submitted2013
dc.identifier.citationPark, Daniel John. 2013. Evolutionary Adaptation and Antimalarial Resistance in Plasmodium falciparum. Doctoral dissertation, Harvard University.en_US
dc.identifier.otherhttp://dissertations.umi.com/gsas.harvard:11088en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11169775
dc.description.abstractThe malaria parasite, Plasmodium falciparum, has a demonstrated history of adaptation to antimalarials and host immune pressure. This ability unraveled global eradication programs fifty years ago and seriously threatens renewed efforts today. Despite the magnitude of the global health problem, little is known about the genetic mechanisms by which the parasite evades control efforts. Population genomic methods provide a new way to identify the mutations and genes responsible for drug resistance and other clinically important traits.en_US
dc.language.isoen_USen_US
dash.licenseLAA
dc.subjectEvolution & developmenten_US
dc.subjectGeneticsen_US
dc.subjectParasitologyen_US
dc.subjectdrug resistanceen_US
dc.subjectevolutionen_US
dc.subjectgenomicsen_US
dc.subjectGWASen_US
dc.subjectmalariaen_US
dc.subjectselectionen_US
dc.titleEvolutionary Adaptation and Antimalarial Resistance in Plasmodium falciparumen_US
dc.typeThesis or Dissertationen_US
dash.depositing.authorPark, Daniel John
dc.date.available2013-10-14T14:50:07Z
thesis.degree.date2013en_US
thesis.degree.disciplineBiology, Organismic and Evolutionaryen_US
thesis.degree.grantorHarvard Universityen_US
thesis.degree.leveldoctoralen_US
thesis.degree.namePh.D.en_US
dc.contributor.committeeMemberSabeti, Pardisen_US
dc.contributor.committeeMemberHartl, Danielen_US
dc.contributor.committeeMemberWakeley, Johnen_US
dc.contributor.committeeMemberWirth, Dyannen_US
dash.contributor.affiliatedPark, Daniel John


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