Functional Genomics Approaches to Identify and Characterize Oncogenic Signaling
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CitationShao, Diane Donghui. 2013. Functional Genomics Approaches to Identify and Characterize Oncogenic Signaling. Doctoral dissertation, Harvard University.
AbstractOncogenes drive cancer by hijacking normal cellular functions involved in proliferation and survival. Suppression of the driving oncogene is highly effective for promoting tumor regression, a phenomenon termed "oncogenic addiction." By using unbiased genetic tools to functionally probe oncogenic addiction, we can identify cancer dependencies and characterize aspects of oncogenic signaling.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11169824
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