Analysis of genetic systems using experimental evolution and whole-genome sequencing

 
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Hegreness, Matthew
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https://doi.org/10.1186/gb-2007-8-1-201
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Hegreness, Matthew and Roy Kishony. 2007. Analysis of genetic systems using experimental evolution and whole-genome sequencing. Genome Biology 8(1): 201.
Abstract
The application of whole-genome sequencing to the study of microbial evolution promises to reveal the complex functional networks of mutations that underlie adaptation. A recent study of parallel evolution in populations of Escherichia coli shows how adaptation involves both functional changes to specific proteins as well as global changes in regulation.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839123/pdf/
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This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
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http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181063

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