Discovery and Characterization of Novel Bioactive Peptides and a Natural ERRalpha Ligand
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Schwaid, Adam. 2013. Discovery and Characterization of Novel Bioactive Peptides and a Natural ERRalpha Ligand. Doctoral dissertation, Harvard University.Abstract
Metabolites and peptides have a central role in biology that is often overlooked. Despite the importance of metabolites in key protein-metabolite interactions (PMIs), the extent and identity of these interactions is not known. Likewise, the extent to which short open reading frames (sORFs) in the genome are translated into peptides has also been an elusive question. This dissertation describes the development and application of methods to elucidate unknown molecules and interactions critical to understanding biology, and the subsequent characterization of the biological roles of these discoveries in cells and mice.Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAACitable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181064
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