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dc.contributor.authorPregno, Giulia
dc.contributor.authorFrola, Elena
dc.contributor.authorGraziano, Stefania
dc.contributor.authorPatrizi, Annarita
dc.contributor.authorBussolino, Federico
dc.contributor.authorArese, Marco
dc.contributor.authorSassoè-Pognetto, Marco
dc.date.accessioned2013-10-18T12:42:27Z
dc.date.issued2013
dc.identifier.citationPregno, Giulia, Elena Frola, Stefania Graziano, Annarita Patrizi, Federico Bussolino, Marco Arese, and Marco Sassoè-Pognetto. 2013. Differential regulation of neurexin at glutamatergic and gabaergic synapses. Frontiers in Cellular Neuroscience 7:35.en_US
dc.identifier.issn1662-5102en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11181091
dc.description.abstractNeurexins (Nrxs) have emerged as potential determinants of synaptic specificity, but little is known about their localization at central synapses. Here we show that Nrxs have a remarkably selective localization at distinct types of glutamatergic synapses and we reveal an unexpected ontogenetic regulation of Nrx expression at GABAergic synapses. Our data indicate that synapses are specified by molecular interactions that involve both Nrx-dependent and Nrx-independent mechanisms. We propose that differences in the spatio-temporal profile of Nrx expression may contribute to specify the molecular identity of synapses.en_US
dc.language.isoen_USen_US
dc.publisherFrontiers Media S.A.en_US
dc.relation.isversionofdoi:10.3389/fncel.2013.00035en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616244/pdf/en_US
dash.licenseLAA
dc.subjectneurexinen_US
dc.subjectneuroliginen_US
dc.subjectGABAen_US
dc.subjectsynaptic specificityen_US
dc.subjectcerebellumen_US
dc.titleDifferential regulation of neurexin at glutamatergic and GABAergic synapsesen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalFrontiers in Cellular Neuroscienceen_US
dash.depositing.authorPatrizi, Annarita
dc.date.available2013-10-18T12:42:27Z
dc.identifier.doi10.3389/fncel.2013.00035*
dash.contributor.affiliatedPatrizi, Annarita


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