In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours

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In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours

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Title: In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
Author: Kwon, Young-Min; Mellon, S. J.; Monk, P.; Murray, D. W.; Gill, H. S.

Note: Order does not necessarily reflect citation order of authors.

Citation: Kwon, Y-M., S. J. Mellon, P. Monk, D. W. Murray, and H. S. Gill. 2012. In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours. Bone & Joint Research 1(4): 42-49.
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Abstract: Objectives: Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities. Methods: The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans. Results: Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02). Conclusions: The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours.
Published Version: doi:10.1302/2046-3758.14.2000019
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626206/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181170
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