Sequencing by Hybridization of Long Targets

DSpace/Manakin Repository

Sequencing by Hybridization of Long Targets

Citable link to this page


Title: Sequencing by Hybridization of Long Targets
Author: Qin, Yu; Schneider, Tobias M; Brenner, Michael P.

Note: Order does not necessarily reflect citation order of authors.

Citation: Qin, Yu, Tobias M. Schneider, and Michael P. Brenner. 2012. Sequencing by hybridization of long targets. PLoS ONE 7(5): e35819.
Full Text & Related Files:
Abstract: Sequencing by Hybridization (SBH) reconstructs an n-long target DNA sequence from its biochemically determined \(l\)-long subsequences. In the standard approach, the length of a uniformly random sequence that can be unambiguously reconstructed is limited to \(n=O(2^{l})\) due to repetitive subsequences causing reconstruction degeneracies. We present a modified sequencing method that overcomes this limitation without the need for different types of biochemical assays and is robust to error.
Published Version: doi:10.1371/journal.pone.0035819
Other Sources:
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at
Citable link to this page:
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)


Search DASH

Advanced Search