dc.contributor.author | Gudelj, Ivana | |
dc.contributor.author | Weitz, Joshua S | |
dc.contributor.author | Ferenci, Tom | |
dc.contributor.author | Claire Horner-Devine, M | |
dc.contributor.author | Marx, Christopher J | |
dc.contributor.author | Meyer, Justin R | |
dc.contributor.author | Forde, Samantha E | |
dc.date.accessioned | 2013-10-24T20:40:46Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Gudelj, Ivana, Joshua S. Weitz, Tom Ferenci, M. Claire Horner-Devine, Christopher J. Marx, Justin R. Meyer, and Samantha E. Forde. 2010. An integrative approach to understanding microbial diversity: from intracellular mechanisms to community structure. Ecology Letters 13(9): 1073-1084. | en_US |
dc.identifier.issn | 1461-023X | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:11211549 | |
dc.description.abstract | Trade-offs have been put forward as essential to the generation and maintenance of diversity. However, variation in trade-offs is often determined at the molecular level, outside the scope of conventional ecological inquiry. In this study, we propose that understanding the intracellular basis for trade-offs in microbial systems can aid in predicting and interpreting patterns of diversity. First, we show how laboratory experiments and mathematical models have unveiled the hidden intracellular mechanisms underlying trade-offs key to microbial diversity: (i) metabolic and regulatory tradeoffs in bacteria and yeast; (ii) life-history trade-offs in bacterial viruses. Next, we examine recent studies of marine microbes that have taken steps toward reconciling the molecular and the ecological views of trade-offs, despite the challenges in doing so in natural settings. Finally, we suggest avenues for research where mathematical modelling,
experiments and studies of natural microbial communities provide a unique opportunity to integrate studies of diversity across multiple scales. | en_US |
dc.description.sponsorship | Organismic and Evolutionary Biology | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Blackwell Publishing Ltd. | en_US |
dc.relation.isversionof | doi://10.1111/j.1461-0248.2010.01507.x | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069490/pdf/ | en_US |
dash.license | LAA | |
dc.subject | ecological genomics | en_US |
dc.subject | experimental evolution | en_US |
dc.subject | mathematical models | en_US |
dc.subject | micro-organisms | en_US |
dc.subject | metabolism | en_US |
dc.subject | parasitism | en_US |
dc.subject | trade-offs | en_US |
dc.subject | viruses | en_US |
dc.title | An Integrative Approach to Understanding Microbial Diversity: From Intracellular Mechanisms to Community Structure | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Ecology Letters | en_US |
dash.depositing.author | Marx, Christopher J | |
dc.date.available | 2013-10-24T20:40:46Z | |
dc.identifier.doi | 10.1111/j.1461-0248.2010.01507.x | * |
dash.contributor.affiliated | Marx, Christopher J | |