# Genetic Architecture of Flowering-Time Variation in Arabidopsis thaliana

 Title: Genetic Architecture of Flowering-Time Variation in Arabidopsis thaliana Author: Salomé, Patrice A.; Bomblies, Kirsten; Laitinen, Roosa A.; Yant, Levi; Mott, Richard; Weigel, Detlef Note: Order does not necessarily reflect citation order of authors. Citation: Salomé, Patrice A., Kirsten Bomblies, Roosa A. E. Laitinen, Levi Yant, Richard Mott, and Detlef Weigel. 2011. Genetic Architecture of Flowering-Time Variation in Arabidopsis thaliana. Genetics 188(2): 421-433. Full Text & Related Files: Salome_Genetics_2011_0.pdf (2.847Mb; PDF) Abstract: The onset of flowering is an important adaptive trait in plants. The small ephemeral species Arabidopsis thaliana grows under a wide range of temperature and day-length conditions across much of the Northern hemisphere, and a number of flowering-time loci that vary between different accessions have been identified before. However, only few studies have addressed the species-wide genetic architecture of flowering time control. We have taken advantage of a set of 18 distinct accessions that present much of the common genetic diversity of A. thaliana and mapped quantitative trait loci (QTL) for flowering time in 17 $$F_2$$ populations derived from these parents. We found that the majority of flowering-time QTL cluster in as few as five genomic regions, which include the locations of the entire FLC/MAF clade of transcription factor genes. By comparing effects across shared parents, we conclude that in several cases there might be an allelic series caused by rare alleles. While this finding parallels results obtained for maize, in contrast to maize much of the variation in flowering time in A. thaliana appears to be due to large-effect alleles. Published Version: doi:10.1534/genetics.111.126607 Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122318/ Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11213593 Downloads of this work: