The Application of Optical Coherence Tomography in Musculoskeletal Disease

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The Application of Optical Coherence Tomography in Musculoskeletal Disease

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Title: The Application of Optical Coherence Tomography in Musculoskeletal Disease
Author: Rashidifard, Christopher; Vercollone, Christopher; Martin, Scott David; Liu, Bin; Brezinski, Mark Edward

Note: Order does not necessarily reflect citation order of authors.

Citation: Rashidifard, Christopher, Christopher Vercollone, Scott Martin, Bin Liu, and Mark E. Brezinski. 2013. The application of optical coherence tomography in musculoskeletal disease. Arthritis 2013: 563268.
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Abstract: Many musculoskeletal disorders (MDs) are associated with irreversible bone and cartilage damage; this is particularly true for osteoarthritis (OA). Therefore, a clinical need exists for modalities which can detect OA and other MDs at early stages. Optical coherence tomography (OCT) is an infrared-based imaging, currently FDA approved in cardiology and ophthalmology, which has a resolution greater than 10 microns and acquisition rate of 120 frames/second. It has shown feasibility for imaging early OA, identifying changes prior to cartilage thinning both in vitro and in vivo in patients and in OA animal models. In addition, OCT has shown an ability to identify early rheumatoid arthritis (RA) and guide tendon repair, but has the potential for an even greater impact. Clinical trials in OA are currently underway, as well as in several other MDs.
Published Version: doi:10.1155/2013/563268
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568691/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11215056
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