Reconstructing Native American Population History

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Patterson, Nick
Campbell, Desmond
Mazieres, Stéphane
Ray, Nicolas
Parra, Maria V.
Rojas, Winston
Duque, Constanza
Mesa, Natalia
García, Luis F.
Triana, Omar
Blair, Silvia
Maestre, Amanda
Dib, Juan C.
Bravi, Claudio M.
Bailliet, Graciela
Corach, Daniel
Hünemeier, Tábita
Bortolini, Maria-Cátira
Salzano, Francisco M.
Petzl-Erler, María Luiza
Acuña-Alonzo, Victor
Aguilar-Salinas, Carlos
Canizales-Quinteros, Samuel
Tusié-Luna, Teresa
Riba, Laura
Rodríguez-Cruz, Maricela
Lopez-Alarcón, Mardia
Coral-Vazquez, Ramón
Canto-Cetina, Thelma
Silva-Zolezzi, Irma
Fernandez-Lopez, Juan Carlos
Contreras, Alejandra V.
Jimenez-Sanchez, Gerardo
Gómez-Vázquez, María José
Molina, Julio
Carracedo, Ángel
Salas, Antonio
Gallo, Carla
Poletti, Giovanni
Witonsky, David B.
Alkorta-Aranburu, Gorka
Sukernik, Rem I.
Osipova, Ludmila
Fedorova, Sardana
Vasquez, René
Villena, Mercedes
Moreau, Claudia
Barrantes, Ramiro
Excoffier, Laurent
Bedoya, Gabriel
Rothhammer, Francisco
Dugoujon, Jean Michel
Larrouy, Georges
Klitz, William
Labuda, Damian
Kidd, Judith
Kidd, Kenneth
Rienzo, Anna Di
Freimer, Nelson B.
Ruiz-Linares, Andrés
Note: Order does not necessarily reflect citation order of authors.
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https://doi.org/10.1038/nature11258Metadata
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Reich, David, Nick Patterson, Desmond Campbell, Arti Tandon, Stéphane Mazieres, Nicolas Ray, Maria V. Parra, et al. 2013. Reconstructing native american population history. Nature 488(7411): 370-374.Abstract
The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved1–5. One contentious issue is whether the settlement occurred via a single6–8 or multiple streams of migration from Siberia9–15. The pattern of dispersals within the Americas is also poorly understood. To address these questions at higher resolution than was previously possible, we assembled data from 52 Native American and 17 Siberian groups genotyped at 364,470 single nucleotide polymorphisms. We show that Native Americans descend from at least three streams of Asian gene flow. Most descend entirely from a single ancestral population that we call “First American”. However, speakers of Eskimo-Aleut languages from the Arctic inherit almost half their ancestry from a second stream of Asian gene flow, and the Na-Dene-speaking Chipewyan from Canada inherit roughly one-tenth of their ancestry from a third stream. We show that the initial peopling followed a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America. A major exception is in Chibchan-speakers on both sides of the Panama Isthmus, who have ancestry from both North and South America.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615710/pdf/Terms of Use
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