Of flies and men: insights on organismal metabolism from fruit flies

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Of flies and men: insights on organismal metabolism from fruit flies

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Title: Of flies and men: insights on organismal metabolism from fruit flies
Author: Rajan, Akhila; Perrimon, Norbert

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Citation: Rajan, Akhila, and Norbert Perrimon. 2013. Of flies and men: insights on organismal metabolism from fruit flies. BMC Biology 11: 38.
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Abstract: The fruit fly Drosophila has contributed significantly to our general understanding of the basic principles of signaling, cell and developmental biology, and neurobiology. However, answers to questions pertaining to energy metabolism have been so far mostly addressed in more complex model organisms such as mice. We review in this article recent studies that show how the genetic tractability and simplicity of Drosophila are being used to identify novel regulatory mechanisms at the organismal level, and to query the co-ordination between energy metabolism and other processes such as neurodegeneration, circadian rhythms, immunity, and tumor biology.
Published Version: doi:10.1186/1741-7007-11-38
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626883/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11235991
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