Of flies and men: insights on organismal metabolism from fruit flies
| Title: | Of flies and men: insights on organismal metabolism from fruit flies |
| Author: |
Rajan, Akhila; Perrimon, Norbert
Note: Order does not necessarily reflect citation order of authors. |
| Citation: | Rajan, Akhila, and Norbert Perrimon. 2013. Of flies and men: insights on organismal metabolism from fruit flies. BMC Biology 11: 38. |
| Full Text & Related Files: |
3626883.pdf (635.4Kb; PDF) 
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| Abstract: | The fruit fly Drosophila has contributed significantly to our general understanding of the basic principles of signaling, cell and developmental biology, and neurobiology. However, answers to questions pertaining to energy metabolism have been so far mostly addressed in more complex model organisms such as mice. We review in this article recent studies that show how the genetic tractability and simplicity of Drosophila are being used to identify novel regulatory mechanisms at the organismal level, and to query the co-ordination between energy metabolism and other processes such as neurodegeneration, circadian rhythms, immunity, and tumor biology. |
| Published Version: | doi:10.1186/1741-7007-11-38 |
| Other Sources: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626883/pdf/ |
| Terms of Use: | This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA |
| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:11235991 |
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