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dc.contributor.authorSavitz, J B
dc.contributor.authorRauch, Scott Laurence
dc.contributor.authorDrevets, W C
dc.date.accessioned2013-11-04T19:41:57Z
dc.date.issued2013
dc.identifier.citationSavitz, J B, S L Rauch, and W C Drevets. 2013. Clinical application of brain imaging for the diagnosis of mood disorders: the current state of play. Molecular Psychiatry 18(5): 528-539.en_US
dc.identifier.issn1359-4184en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11266831
dc.description.abstractIn response to queries about whether brain imaging technology has reached the point where it is useful for making a clinical diagnosis and for helping to guide treatment selection, the American Psychiatric Association (APA) has recently written a position paper on the Clinical Application of Brain Imaging in Psychiatry. The following perspective piece is based on our contribution to this APA position paper, which specifically emphasized the application of neuroimaging in mood disorders. We present an introductory overview of the challenges faced by researchers in developing valid and reliable biomarkers for psychiatric disorders, followed by a synopsis of the extant neuroimaging findings in mood disorders, and an evidence-based review of the current research on brain imaging biomarkers in adult mood disorders. Although there are a number of promising results, by the standards proposed below, we argue that there are currently no brain imaging biomarkers that are clinically useful for establishing diagnosis or predicting treatment outcome in mood disorders.en_US
dc.language.isoen_USen_US
dc.publisherNature Publishing Groupen_US
dc.relation.isversionofdoi:10.1038/mp.2013.25en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633788/pdf/en_US
dash.licenseLAA
dc.subjectbiomarkeren_US
dc.subjectdepressionen_US
dc.subjectdiagnosisen_US
dc.subjectmood disordersen_US
dc.subjectMRIen_US
dc.subjectneuroimagingen_US
dc.titleClinical application of brain imaging for the diagnosis of mood disorders: the current state of playen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalMolecular Psychiatryen_US
dash.depositing.authorRauch, Scott Laurence
dc.date.available2013-11-04T19:41:57Z
dc.identifier.doi10.1038/mp.2013.25*
dash.contributor.affiliatedRauch, Scott


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