Feasibility of aortic valve assessment with low dose prospectively triggered adaptive systolic (PTAS) cardiac computed tomography angiography

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Feasibility of aortic valve assessment with low dose prospectively triggered adaptive systolic (PTAS) cardiac computed tomography angiography

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Title: Feasibility of aortic valve assessment with low dose prospectively triggered adaptive systolic (PTAS) cardiac computed tomography angiography
Author: Lee, Ashley M; Beaudoin, Jonathan; Thai, Wai-Ee; Wai, Bryan; Hui, Gladwin C; Sidhu, Manavjot S; Engel, Leif-Christopher; Abbara, Suhny; Hoffmann, Udo; Ghoshhajra, Brian Burns

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Citation: Lee, Ashley M, Jonathan Beaudoin, Wai-Ee Thai, Bryan Wai, Gladwin C Hui, Manavjot S Sidhu, Leif-Christopher Engel, Suhny Abbara, Udo Hoffmann, and Brian B Ghoshhajra. 2013. Feasibility of aortic valve assessment with low dose prospectively triggered adaptive systolic (ptas) cardiac computed tomography angiography. BMC Research Notes 6: 158.
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Abstract: Background: Cardiac computed tomography angiography (CTA) is feasible for aortic valve evaluation, but retrospective gated protocols required high radiation doses for aortic valve assessment. A prospectively triggered adaptive systolic (PTAS) cardiac CT protocol was recently described in arrhythmia using second-generation dual-source CT. In this study, we sought to evaluate the feasibility of PTAS CTA to assess the aortic valve at a low radiation dose. Findings: A retrospective cohort of 29 consecutive patients whom underwent PTAS protocols for clinical indications other than aortic valve assessment and whom also received echocardiography within 2 months of CT, was identified. Images were reviewed for aortic valve morphology (tricuspid/bicuspid/prosthetic) and stenosis (AS) by experienced blinded readers. Accuracy versus echocardiography and radiation doses were assessed. All PTAS coronary CTAs were clinically diagnostic with 0 un-evaluable coronary segments. The accuracy of PTAS for aortic valve morphology was 92.6%, and for exclusion of severe AS was 93.1%. Two exams were un-evaluable for the aortic valve due to inadequate number of phases archived for interpretation. Total radiation dose was a median of 2.8 mSv (interquartile range 1.4–4.4 mSv). Conclusions: PTAS CTA protocols using second-generation dual-source CT for aortic valve evaluation are feasible at low doses. This protocol should be investigated further in larger cohorts.
Published Version: doi:10.1186/1756-0500-6-158
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640955/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11357499
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