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dc.contributor.authorSegata, Nicola
dc.contributor.authorWaldron, Levi D.
dc.contributor.authorBallarini, Annalisa
dc.contributor.authorNarasimhan, Vagheesh
dc.contributor.authorJousson, Olivier
dc.contributor.authorHuttenhower, Curtis
dc.date.accessioned2013-12-11T19:36:33Z
dc.date.issued2012
dc.identifier.citationSegata, Nicola, Levi Waldron, Annalisa Ballarini, Vagheesh Narasimhan, Olivier Jousson, and Curtis Huttenhower. 2012. Metagenomic microbial community profiling using unique clade-specific marker genes. Nature methods 9(8): 811-814.en_US
dc.identifier.issn1548-7091en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11369874
dc.description.abstractMetagenomic shotgun sequencing data can identify microbes populating a microbial community and their proportions, but existing taxonomic profiling methods are inefficient for increasingly large datasets. We present an approach that uses clade-specific marker genes to unambiguously assign reads to microbial clades more accurately and >50× faster than current approaches. We validated MetaPhlAn on terabases of short reads and provide the largest metagenomic profiling to date of the human guten_US
dc.language.isoen_USen_US
dc.relation.isversionofdoi:10.1038/nmeth.2066en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443552/pdf/en_US
dash.licenseLAA
dc.titleMetagenomic microbial community profiling using unique clade-specific marker genesen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalNature methodsen_US
dash.depositing.authorWaldron, Levi D.
dc.date.available2013-12-11T19:36:33Z
dc.identifier.doi10.1038/nmeth.2066*
dash.contributor.affiliatedNarasimhan, Vagheesh
dash.contributor.affiliatedWaldron, Levi
dash.contributor.affiliatedHuttenhower, Curtis
dc.identifier.orcid0000-0002-1110-0096


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