Predictors of stunting, wasting, and underweight among Tanzanian children born to HIV-infected women
McDonald, Christine M.
Manji, Karim P.
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CitationMcDonald, Christine M., Roland Kupka, Karim P. Manji, James Okuma, Ronald J. Bosch, Said Aboud, Rodrick Kisenge, Donna Spiegelman, Wafaie W. Fawzi, and Christopher P. Duggan. 2012. Predictors of stunting, wasting, and underweight among tanzanian children born to hiv-infected women. European journal of clinical nutrition 66(11): 1265-1276.
AbstractBackground: Children born to HIV-infected women are susceptible to undernutrition, but modifiable risk factors and the time course of the development of undernutrition have not been well characterized. Objective: To identify maternal, socioeconomic, and child characteristics that are associated with stunting, wasting, and underweight among Tanzanian children born to HIV-infected mothers, followed from 6 weeks for 24 months. Methods: Maternal and socioeconomic characteristics were recorded during pregnancy, data pertaining to the infant’s birth were collected immediately after delivery, morbidity histories and anthropometric measurements were performed monthly. Multivariate Cox proportional hazards methods were used to assess the association between potential predictors and the time to first episode of stunting, wasting, and underweight. Results: 2387 infants (54.0% male) were enrolled and followed for a median duration of 21.2 months. The respective prevalence of prematurity (<37 weeks) and low birthweight (<2500g) was 15.2% and 7.0%; 11.3% of infants were HIV-positive at 6 weeks. Median time to first episode of stunting, wasting, and underweight was 8.7, 7.2, and 7.0 months, respectively. Low maternal education, few household possessions, low infant birthweight, child HIV infection and male sex were all independent predictors of stunting, wasting, and underweight. In addition, preterm infants were more likely to become wasted and underweight, whereas those with a low Apgar score at birth were more likely to become stunted. Conclusion: Interventions to improve maternal education and nutritional status, reduce mother-to-child transmission of HIV, and increase birth weight may lower the risk of undernutrition among children born to HIV-infected women.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11379645
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