Problems with the report of the expert panel on blood cholesterol levels in children and adolescents

DSpace/Manakin Repository

Problems with the report of the expert panel on blood cholesterol levels in children and adolescents

Citable link to this page

 

 
Title: Problems with the report of the expert panel on blood cholesterol levels in children and adolescents
Author: Newman, Thomas B.; Garber, Alan M; Holtzman, Neil A.; Hulley, Stephen B.

Note: Order does not necessarily reflect citation order of authors.

Citation: Newman, Thomas B., Alan M. Garber, Neil A. Holtzman, and Stephen B. Hulley. 1995. Problems with the report of the expert panel on blood cholesterol levels in children and adolescents. Archives of Pediatrics & Adolescent Medicine 149, 3:241-247.
Access Status: Full text of the requested work is not available in DASH at this time (“dark deposit”). For more information on dark deposits, see our FAQ.
Full Text & Related Files:
Abstract: An Expert Panel convened by the National Cholesterol Education Program has recommended selective screening and treatment of children for high blood cholesterol levels, based on family history of cardiovascular disease or high blood cholesterol. This recommendation is problematic for several reasons. First, the recommended diets are likely to cause only a slight decrease in low-density lipoprotein cholesterol levels, the projected benefits of which will be offset by a similar decrease in high-density lipoprotein cholesterol levels. Lack of efficacy of the recommended diets could lead to use of more restrictive diets or to cholesterol lowering drugs. Second, even under optimistic assumptions, beneficial effects of cholesterol intervention will be small and delayed for many decades. As a result, childhood cholesterol-lowering efforts will not be cost-effective. Third, the Expert Panel's recommendations do not address important gender differences. Girls have higher average cholesterol levels than boys. They will therefore qualify for more dietary and drug treatment despite their lower age-adjusted risk of heart disease and the lack of association between cholesterol levels and cardiovascular mortality in women. Finally, recent evidence from randomized trials, cohort studies, and animal experiments suggests that cholesterol lowering may have serious adverse effects. This evidence was not discussed in the Expert Panel's report. Given current evidence, any screening and treatment of children for high blood cholesterol levels is, at best, premature.
Published Version: 10.1001/archpedi.1995.02170150021003
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11595729
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters