A discrete-time model of the acquisition of antibiotic-resistant infections in hospitalized patients

 
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https://doi.org/10.2307/2531684
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Garber, Alan M. 1989. A discrete-time model of the acquisition of antibiotic-resistant infections in hospitalized patients. Biometrics 45, no. 3:797-816.
Abstract
Antibiotic use is thought to promote bacterial antibiotic resistance by selectively inhibiting the growth of sensitive strains. This study investigates the relation between antibiotic use and the propagation of
antibiotic-resistant hospital-acquired infections due to gram-negative bacteria in a population of
hospitalized patients. It treats infection spread and hospital mortality as a Markov process, in which
the transition probabilities are logistic functions of a set of personal and hospital characteristics. Data
from a university hospital are used to derive the parameters of the model.
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http://nrs.harvard.edu/urn-3:HUL.InstRepos:11595739

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