dc.contributor.author | Korobkova, Ekaterina A. | |
dc.contributor.author | Emonet, Thierry | |
dc.contributor.author | Park, Heungwon | |
dc.contributor.author | Cluzel, Philippe | |
dc.date.accessioned | 2014-02-10T20:33:58Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | Korobkova, Ekaterina A., Thierry Emonet, Heungwon Park, and Philippe Cluzel. 2006. Hidden stochastic nature of a single bacterial motor. Physical Review Letters 96, no. 5: 058105. | en_US |
dc.identifier.issn | 0031-9007 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:11688765 | |
dc.description.abstract | The rotary flagellar motor of Escherichia coli bacterium switches stochastically between the clockwise (CW) and counterclockwise (CCW) direction. We found that the CW and CCW intervals could be described by a gamma distribution, suggesting the existence of hidden Markov steps preceding each motor switch. Power spectra of time series of switching events exhibited a peaking frequency instead of the Lorentzian profile expected from standard kinetic two-state models. Our analysis indicates that the number of hidden steps may be a key dynamical parameter underlying the switching process in a single bacterial motor as well as in large cooperative molecular systems. | en_US |
dc.description.sponsorship | Molecular and Cellular Biology | en_US |
dc.description.sponsorship | Physics | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | American Physical Society | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1103/PhysRevLett.96.058105 | en_US |
dash.license | LAA | |
dc.subject | Markov processes | en_US |
dc.subject | molecular biophysics | en_US |
dc.subject | biochemistry | en_US |
dc.subject | microorganism | en_US |
dc.title | Hidden Stochastic Nature of a Single Bacterial Motor | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Physical Review Letters | en_US |
dash.depositing.author | Cluzel, Philippe | |
dc.date.available | 2014-02-10T20:33:58Z | |
dc.identifier.doi | 10.1103/PhysRevLett.96.058105 | * |
dash.contributor.affiliated | Cluzel, Philippe | |