Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

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Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

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Title: Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology
Author: Tsai, Tsung-Han; Potsaid, Benjamin; Tao, Yuankai K.; Jayaraman, Vijaysekhar; Jiang, James; Heim, Peter J. S.; Kraus, Martin F.; Zhou, Chao; Hornegger, Joachim; Mashimo, Hiroshi; Cable, Alex E.; Fujimoto, James G.

Note: Order does not necessarily reflect citation order of authors.

Citation: Tsai, T., B. Potsaid, Y. K. Tao, V. Jayaraman, J. Jiang, P. J. S. Heim, M. F. Kraus, et al. 2013. “Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology.” Biomedical Optics Express 4 (7): 1119-1132. doi:10.1364/BOE.4.001119. http://dx.doi.org/10.1364/BOE.4.001119.
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Abstract: We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed endoscopic swept source optical coherence tomography (OCT) using a vertical cavity surface-emitting laser (VCSEL) at a 1 MHz axial scan rate. The micromotor can rotate a micro-prism at several hundred frames per second with less than 5 V drive voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back to acquire a three-dimensional (3D) data set covering a large area on the specimen. The VCSEL provides a high axial scan rate to support dense sampling under high frame rate operation. Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 μm axial resolution, 8 μm lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated.
Published Version: doi:10.1364/BOE.4.001119
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704093/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11717682
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