Show simple item record

dc.contributor.authorLengsfeld, Bettina Marie
dc.contributor.authorBerry, Kayla Nicole
dc.contributor.authorGhosh, Sharmistha
dc.contributor.authorTakahashi, Masateru
dc.contributor.authorFrancis, Nicole J.
dc.date.accessioned2014-02-21T16:01:40Z
dc.date.issued2012
dc.identifier.citationLengsfeld, Bettina M., Kayla N. Berry, Sharmistha Ghosh, Masateru Takahashi, and Nicole J. Francis. 2012. A polycomb complex remains bound through dna replication in the absence of other eukaryotic proteins. Scientific Reports 2: 661.en_US
dc.identifier.issn2045-2322en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11729318
dc.description.abstractPropagation of chromatin states through DNA replication is central to epigenetic regulation and can involve recruitment of chromatin proteins to replicating chromatin through interactions with replication fork components. Here we show using a fully reconstituted T7 bacteriophage system that eukaryotic proteins are not required to tether the Polycomb complex PRC1 to templates during DNA replication. Instead, DNA binding by PRC1 can withstand passage of a simple replication fork.en_US
dc.description.sponsorshipMolecular and Cellular Biologyen_US
dc.language.isoen_USen_US
dc.publisherNature Publishing Groupen_US
dc.relation.isversionofdoi:10.1038/srep00661en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443814/pdf/en_US
dash.licenseLAA
dc.titleA Polycomb complex remains bound through DNA replication in the absence of other eukaryotic proteinsen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalScientific Reportsen_US
dash.depositing.authorLengsfeld, Bettina Marie
dc.date.available2014-02-21T16:01:40Z
dc.identifier.doi10.1038/srep00661*
dash.contributor.affiliatedLengsfeld, Bettina Marie
dash.contributor.affiliatedBerry, Kayla


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record