Pregnancy in a Woman with Homozygous Familial Hypercholesterolemia Not on Low-Density Lipoprotein Apheresis
Nassar, Anwar H.
MetadataShow full item record
CitationFahed, Akl C., and Anwar H. Nassar. 2012. “Pregnancy in a Woman with Homozygous Familial Hypercholesterolemia Not on Low-Density Lipoprotein Apheresis.” AJP Reports 2 (1): 33-36. doi:10.1055/s-0032-1305798. http://dx.doi.org/10.1055/s-0032-1305798.
AbstractPregnancy in women with homozygous familial hypercholesterolemia (FH) has been rarely reported and might pose risks on the mother and her fetus. Although most reported cases remained on low-density lipoprotein (LDL) apheresis, there are no clear guidelines regarding the management of this entity. We report the first case of an uncomplicated pregnancy in a 24-year-old homozygous FH woman who was not maintained on LDL apheresis. FH expresses a wide variability in the phenotype, and management of homozygous FH cases who desire to become pregnant should be individualized based on preconceptional assessment with frequent antenatal follow-up. Decisions on management should be made after weighing the risks versus benefits of LDL apheresis.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11855730