Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis

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Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis

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Title: Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis
Author: Morales, Marvin R.; Mellem, Kevin T; Myers, Andrew G.

Note: Order does not necessarily reflect citation order of authors.

Citation: Morales, Marvin R., Kevin T. Mellem, and Andrew G. Myers. 2012. “Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis.” Angewandte Chemie International Edition 51 (19) (May 7): 4568–4571.
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Abstract: Pseudoephenamine is shown to be a versatile chiral auxiliary for asymmetric synthesis. It is free from regulatory restrictions and exhibits remarkable stereocontrol in alkylation reactions, especially those that form quaternary carbon centers. Amides derived from pseudoephenamine exhibit a high propensity to be crystalline substances and provide sharp, well-defined peaks in NMR spectra.
Published Version: doi:10.1002/anie.201200370
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11870382
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