Analysis of the African coelacanth genome sheds light on tetrapod evolution
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Author
Amemiya, Chris T.
Alföldi, Jessica
Lee, Alison P.
Fan, Shaohua
Philippe, Hervé
MacCallum, Iain
Braasch, Ingo
Manousaki, Tereza
Schneider, Igor
Rohner, Nicolas
Organ, Chris
Chalopin, Domitille
Smith, Jeramiah J.
Robinson, Mark
Dorrington, Rosemary A.
Gerdol, Marco
Aken, Bronwen
Biscotti, Maria Assunta
Barucca, Marco
Baurain, Denis
Berlin, Aaron M.
Blatch, Gregory L.
Buonocore, Francesco
Burmester, Thorsten
Campbell, Michael S.
Canapa, Adriana
Cannon, John P.
Christoffels, Alan
De Moro, Gianluca
Edkins, Adrienne L.
Fan, Lin
Fausto, Anna Maria
Feiner, Nathalie
Forconi, Mariko
Gamieldien, Junaid
Gnerre, Sante
Gnirke, Andreas
Goldstone, Jared V.
Haerty, Wilfried
Hahn, Mark E.
Hesse, Uljana
Hoffmann, Steve
Johnson, Jeremy
Karchner, Sibel I.
Kuraku, Shigehiro
Lara, Marcia
Litman, Gary W.
Mauceli, Evan
Miyake, Tsutomu
Mueller, M. Gail
Nelson, David R.
Nitsche, Anne
Olmo, Ettore
Ota, Tatsuya
Pallavicini, Alberto
Panji, Sumir
Picone, Barbara
Ponting, Chris P.
Prohaska, Sonja J.
Przybylski, Dariusz
Saha, Nil Ratan
Ravi, Vydianathan
Ribeiro, Filipe J.
Sauka-Spengler, Tatjana
Scapigliati, Giuseppe
Searle, Stephen M. J.
Sharpe, Ted
Simakov, Oleg
Stadler, Peter F.
Stegeman, John J.
Sumiyama, Kenta
Tabbaa, Diana
Tafer, Hakim
Turner-Maier, Jason
van Heusden, Peter
White, Simon
Williams, Louise
Yandell, Mark
Brinkmann, Henner
Volff, Jean-Nicolas
Shubin, Neil
Schartl, Manfred
Jaffe, David
Postlethwait, John H.
Venkatesh, Byrappa
Di Palma, Federica
Meyer, Axel
Lindblad-Toh, Kerstin
Note: Order does not necessarily reflect citation order of authors.
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https://doi.org/10.1038/nature12027Metadata
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Amemiya, C. T., J. Alföldi, A. P. Lee, S. Fan, H. Philippe, I. MacCallum, I. Braasch, et al. 2013. “Analysis of the African coelacanth genome sheds light on tetrapod evolution.” Nature 496 (7445): 311-316. doi:10.1038/nature12027. http://dx.doi.org/10.1038/nature12027.Abstract
It was a zoological sensation when a living specimen of the coelacanth was first discovered in 1938, as this lineage of lobe-finned fish was thought to have gone extinct 70 million years ago. The modern coelacanth looks remarkably similar to many of its ancient relatives, and its evolutionary proximity to our own fish ancestors provides a glimpse of the fish that first walked on land. Here we report the genome sequence of the African coelacanth, Latimeria chalumnae. Through a phylogenomic analysis, we conclude that the lungfish, and not the coelacanth, is the closest living relative of tetrapods. Coelacanth protein-coding genes are significantly more slowly evolving than those of tetrapods, unlike other genomic features . Analyses of changes in genes and regulatory elements during the vertebrate adaptation to land highlight genes involved in immunity, nitrogen excretion and the development of fins, tail, ear, eye, brain, and olfaction. Functional assays of enhancers involved in the fin-to-limb transition and in the emergence of extra-embryonic tissues demonstrate the importance of the coelacanth genome as a blueprint for understanding tetrapod evolution.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633110/pdf/Terms of Use
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http://nrs.harvard.edu/urn-3:HUL.InstRepos:11878870
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