Polymorphic Amplified Typing Sequences (PATS) Strain Typing System Accurately Discriminates a Set of Temporally and Spatially Disparate Escherichia coli O157 Isolates Associated with Human Infection

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Polymorphic Amplified Typing Sequences (PATS) Strain Typing System Accurately Discriminates a Set of Temporally and Spatially Disparate Escherichia coli O157 Isolates Associated with Human Infection

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Title: Polymorphic Amplified Typing Sequences (PATS) Strain Typing System Accurately Discriminates a Set of Temporally and Spatially Disparate Escherichia coli O157 Isolates Associated with Human Infection
Author: Kudva, Indira T.; Smole, Sandra; Griffin, Robert W.; Garren, Jeonifer; Kalia, Nimisha; Murray, Megan; John, Manohar; Timperi, Ralph; Calderwood, Stephen B.

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Citation: Kudva, Indira T., Sandra Smole, Robert W. Griffin, Jeonifer Garren, Nimisha Kalia, Megan Murray, Manohar John, Ralph Timperi, and Stephen B. Calderwood. 2013. “Polymorphic Amplified Typing Sequences (PATS) Strain Typing System Accurately Discriminates a Set of Temporally and Spatially Disparate Escherichia coli O157 Isolates Associated with Human Infection.” The Open Microbiology Journal 7 (1): 123-129. doi:10.2174/1874285801307010123. http://dx.doi.org/10.2174/1874285801307010123.
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Abstract: Polymorphic Amplified Typing Sequences (PATS) is a PCR-based Escherichia coli O157 (O157) strain typing system. Here, we show that PATS compares excellently with Pulsed-Field Gel Electrophoresis (PFGE) in that both methods cluster geographically diverse O157 isolates similarly. Comparative analysis of the results obtained in this simulated “blind” study attests to the discriminating power and applicability of PATS to epidemiological/nosocomial situations.
Published Version: doi:10.2174/1874285801307010123
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837366/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879005
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