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dc.contributor.authorLam, Thuyen_US
dc.contributor.authorWilliams, Paige L.en_US
dc.contributor.authorBurns, Jane S.en_US
dc.contributor.authorSergeyev, Olegen_US
dc.contributor.authorKorrick, Susan A.en_US
dc.contributor.authorLee, Mary M.en_US
dc.contributor.authorBirnbaum, Linda S.en_US
dc.contributor.authorRevich, Borisen_US
dc.contributor.authorAltshul, Larisa M.en_US
dc.contributor.authorPatterson, Donald G.en_US
dc.contributor.authorTurner, Wayman E.en_US
dc.contributor.authorHauser, Russen_US
dc.date.accessioned2014-03-11T10:15:40Z
dc.date.issued2013en_US
dc.identifier.citationLam, T., P. L. Williams, J. S. Burns, O. Sergeyev, S. A. Korrick, M. M. Lee, L. S. Birnbaum, et al. 2013. “Predictors of Serum Chlorinated Pesticide Concentrations among Prepubertal Russian Boys.” Environmental Health Perspectives 121 (11-12): 1372-1377. doi:10.1289/ehp.1306480. http://dx.doi.org/10.1289/ehp.1306480.en
dc.identifier.issn0091-6765en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11879223
dc.description.abstractBackground: Few studies have evaluated predictors of childhood exposure to organochlorine pesticides (OCPs), a class of lipophilic persistent chemicals. Objectives: Our goal was to identify predictors of serum OCP concentrations—hexachlorobenzene (HCB), β-hexachlorocyclohexane (β-HCH), and p,p-dichlorodiphenyldichloroethylene (p,p´-DDE)—among boys in Chapaevsk, Russia. Methods: Between 2003 and 2005, 499 boys 8–9 years of age were recruited in a prospective cohort. The initial study visit included a physical examination; blood collection; health, lifestyle, and food-frequency questionnaires; and determination of residential distance from a local factory complex that produced HCB and β-HCH. Fasting serum samples were analyzed for OCPs at the U.S. Centers for Disease Control and Prevention. General linear regression models were used to identify predictors of the boys’ serum HCB, β-HCH, and p,p´-DDE concentrations. Results: Among 355 boys with OCP measurements, median serum HCB, β-HCH, and p,p´-DDE concentrations were 158, 167, and 284 ng/g lipid, respectively. Lower body mass index, longer breastfeeding duration, and local dairy consumption were associated with higher concentrations of OCPs. Boys who lived < 2 km from the factory complex had 64% (95% CI: 37, 96) and 57% (95% CI: 32, 87) higher mean HCB and β-HCH concentrations, respectively, than boys who lived ≥ 5 km away. Living > 3 years in Chapaevsk predicted higher β-HCH concentrations, and having parents who lacked a high school education predicted higher p,p´-DDE concentrations. Conclusions: Among this cohort of prepubertal Russian boys, predictors of serum OCPs included consumption of local dairy products, longer local residence, and residential proximity to the local factory complex. Citation: Lam T, Williams PL, Burns JS, Sergeyev O, Korrick SA, Lee MM, Birnbaum LS, Revich B, Altshul LM, Patterson DG Jr, Turner WE, Hauser R. 2013. Predictors of serum chlorinated pesticide concentrations among prepubertal Russian boys. Environ Health Perspect 121:1372–1377; http://dx.doi.org/10.1289/ehp.1306480en
dc.language.isoen_USen
dc.publisherNational Institute of Environmental Health Sciencesen
dc.relation.isversionofdoi:10.1289/ehp.1306480en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855511/pdf/en
dash.licenseLAAen_US
dc.titlePredictors of Serum Chlorinated Pesticide Concentrations among Prepubertal Russian Boysen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalEnvironmental Health Perspectivesen
dash.depositing.authorWilliams, Paige L.en_US
dc.date.available2014-03-11T10:15:40Z
dc.identifier.doi10.1289/ehp.1306480*
dash.authorsorderedfalse
dash.contributor.affiliatedKorrick, Susan
dash.contributor.affiliatedWilliams, Paige
dash.contributor.affiliatedAltshul, Larisa


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