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dc.contributor.authorLi, Jingen_US
dc.contributor.authorNasidze, Ivanen_US
dc.contributor.authorQuinque, Dominiqueen_US
dc.contributor.authorLi, Mingkunen_US
dc.contributor.authorHorz, Hans-Peteren_US
dc.contributor.authorAndré, Claudineen_US
dc.contributor.authorGarriga, Rosa Men_US
dc.contributor.authorHalbwax, Michelen_US
dc.contributor.authorFischer, Anneen_US
dc.contributor.authorStoneking, Marken_US
dc.date.accessioned2014-03-11T10:17:58Z
dc.date.issued2013en_US
dc.identifier.citationLi, Jing, Ivan Nasidze, Dominique Quinque, Mingkun Li, Hans-Peter Horz, Claudine André, Rosa M Garriga, Michel Halbwax, Anne Fischer, and Mark Stoneking. 2013. “The saliva microbiome of Pan and Homo.” BMC Microbiology 13 (1): 204. doi:10.1186/1471-2180-13-204. http://dx.doi.org/10.1186/1471-2180-13-204.en
dc.identifier.issn1471-2180en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11879449
dc.description.abstractBackground: It is increasingly recognized that the bacteria that live in and on the human body (the microbiome) can play an important role in health and disease. The composition of the microbiome is potentially influenced by both internal factors (such as phylogeny and host physiology) and external factors (such as diet and local environment), and interspecific comparisons can aid in understanding the importance of these factors. Results: To gain insights into the relative importance of these factors on saliva microbiome diversity, we here analyze the saliva microbiomes of chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) from two sanctuaries in Africa, and from human workers at each sanctuary. The saliva microbiomes of the two Pan species are more similar to one another, and the saliva microbiomes of the two human groups are more similar to one another, than are the saliva microbiomes of human workers and apes from the same sanctuary. We also looked for the existence of a core microbiome and find no evidence for a taxon-based core saliva microbiome for Homo or Pan. In addition, we studied the saliva microbiome from apes from the Leipzig Zoo, and found an extraordinary diversity in the zoo ape saliva microbiomes that is not found in the saliva microbiomes of the sanctuary animals. Conclusions: The greater similarity of the saliva microbiomes of the two Pan species to one another, and of the two human groups to one another, are in accordance with both the phylogenetic relationships of the hosts as well as with host physiology. Moreover, the results from the zoo animals suggest that novel environments can have a large impact on the microbiome, and that microbiome analyses based on captive animals should be viewed with caution as they may not reflect the microbiome of animals in the wild.en
dc.language.isoen_USen
dc.publisherBioMed Centralen
dc.relation.isversionofdoi:10.1186/1471-2180-13-204en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848470/pdf/en
dash.licenseLAAen_US
dc.titleThe saliva microbiome of Pan and Homoen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalBMC Microbiologyen
dc.date.available2014-03-11T10:17:58Z
dc.identifier.doi10.1186/1471-2180-13-204*
dash.authorsorderedfalse


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