A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors

DSpace/Manakin Repository

A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors

Citable link to this page

 

 
Title: A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors
Author: Damiano, Edward R.; El-Khatib, Firas H.; Zheng, Hui; Nathan, David M.; Russell, Steven J.

Note: Order does not necessarily reflect citation order of authors.

Citation: Damiano, Edward R., Firas H. El-Khatib, Hui Zheng, David M. Nathan, and Steven J. Russell. 2013. “A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors.” Diabetes Care 36 (2): 251-259. doi:10.2337/dc12-0070. http://dx.doi.org/10.2337/dc12-0070.
Full Text & Related Files:
Abstract: OBJECTIVE To compare three continuous glucose monitoring (CGM) devices in subjects with type 1 diabetes under closed-loop blood glucose (BG) control. RESEARCH DESIGN AND METHODS Six subjects with type 1 diabetes (age 52 ± 14 years, diabetes duration 32 ± 14 years) each participated in two 51-h closed-loop BG control experiments in the hospital. Venous plasma glucose (PG) measurements (GlucoScout, International Biomedical) obtained every 15 min (2,360 values) were paired in time with corresponding CGM glucose (CGMG) measurements obtained from three CGM devices, the Navigator (Abbott Diabetes Care), the Seven Plus (DexCom), and the Guardian (Medtronic), worn simultaneously by each subject. Errors in paired PG–CGMG measurements and data reporting percentages were obtained for each CGM device. RESULTS The Navigator had the best overall accuracy, with an aggregate mean absolute relative difference (MARD) of all paired points of 11.8 ± 11.1% and an average MARD across all 12 experiments of 11.8 ± 3.8%. The Seven Plus and Guardian produced aggregate MARDs of all paired points of 16.5 ± 17.8% and 20.3 ± 18.0%, respectively, and average MARDs across all 12 experiments of 16.5 ± 6.7% and 20.2 ± 6.8%, respectively. Data reporting percentages, a measure of reliability, were 76% for the Seven Plus and nearly 100% for the Navigator and Guardian. CONCLUSIONS A comprehensive head-to-head-to-head comparison of three CGM devices for BG values from 36 to 563 mg/dL revealed marked differences in performance characteristics that include accuracy, precision, and reliability. The Navigator outperformed the other two in these areas.
Published Version: doi:10.2337/dc12-0070
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554299/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879824
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters