Immunovirotherapy for the treatment of glioblastoma

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Immunovirotherapy for the treatment of glioblastoma

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Title: Immunovirotherapy for the treatment of glioblastoma
Author: Cheema, Tooba A; Fecci, Peter E; Ning, Jianfang; Rabkin, Samuel D

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Citation: Cheema, Tooba A, Peter E Fecci, Jianfang Ning, and Samuel D Rabkin. 2014. “Immunovirotherapy for the treatment of glioblastoma.” Oncoimmunology 3 (1): e27218. doi:10.4161/onci.27218. http://dx.doi.org/10.4161/onci.27218.
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Abstract: We have recently described a new murine model of glioblastoma, generated by the implantation of syngeneic glioblastoma stem cells into immunocompetent mice, that recapitulates the salient histopathological and immunological features of the human disease. We employed this model to demonstrate the multifaceted activity of an oncolytic herpes simplex virus genetically modified to express interleukin-12, G47∆-IL12.
Published Version: doi:10.4161/onci.27218
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929360/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879877
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