Show simple item record

dc.contributor.authorAhveninen, Jyrkien_US
dc.contributor.authorHuang, Samanthaen_US
dc.contributor.authorNummenmaa, Aapoen_US
dc.contributor.authorBelliveau, John W.en_US
dc.contributor.authorHung, An-Yien_US
dc.contributor.authorJääskeläinen, Iiro P.en_US
dc.contributor.authorRauschecker, Josef P.en_US
dc.contributor.authorRossi, Stephanieen_US
dc.contributor.authorTiitinen, Hannuen_US
dc.contributor.authorRaij, Tommien_US
dc.date.accessioned2014-03-11T13:53:48Z
dc.date.issued2014en_US
dc.identifier.citationAhveninen, Jyrki, Samantha Huang, Aapo Nummenmaa, John W. Belliveau, An-Yi Hung, Iiro P. Jääskeläinen, Josef P. Rauschecker, Stephanie Rossi, Hannu Tiitinen, and Tommi Raij. 2014. “Evidence for distinct human auditory cortex regions for sound location versus identity processing.” Nature communications 4 (1): 2585. doi:10.1038/ncomms3585. http://dx.doi.org/10.1038/ncomms3585.en
dc.identifier.issn2041-1723en
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11879889
dc.description.abstractNeurophysiological animal models suggest that anterior auditory cortex (AC) areas process sound-identity information, whereas posterior ACs specialize in sound location processing. In humans, inconsistent neuroimaging results and insufficient causal evidence have challenged the existence of such parallel AC organization. Here we transiently inhibit bilateral anterior or posterior AC areas using MRI-guided paired-pulse transcranial magnetic stimulation (TMS) while subjects listen to Reference/Probe sound pairs and perform either sound location or identity discrimination tasks. The targeting of TMS pulses, delivered 55–145 ms after Probes, is confirmed with individual-level cortical electric-field estimates. Our data show that TMS to posterior AC regions delays reaction times (RT) significantly more during sound location than identity discrimination, whereas TMS to anterior AC regions delays RTs significantly more during sound identity than location discrimination. This double dissociation provides direct causal support for parallel processing of sound identity features in anterior AC and sound location in posterior AC.en
dc.language.isoen_USen
dc.relation.isversionofdoi:10.1038/ncomms3585en
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932554/pdf/en
dash.licenseLAAen_US
dc.titleEvidence for distinct human auditory cortex regions for sound location versus identity processingen
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden
dc.relation.journalNature communicationsen
dash.depositing.authorAhveninen, Jyrkien_US
dc.date.available2014-03-11T13:53:48Z
dc.identifier.doi10.1038/ncomms3585*
dash.contributor.affiliatedNummenmaa, Aapo
dash.contributor.affiliatedHuang, Samantha
dash.contributor.affiliatedBelliveau, John William
dash.contributor.affiliatedAhveninen, Jyrki
dash.contributor.affiliatedRaij, Tommi


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record